Inhibition of experimental diabetic cataract by topical administration of RS-verapamil hydrochloride

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Inhibition of experimental diabetic cataract by topical administration of RS-verapamil hydrochloride.

AIM To investigate the efficacy of verapamil eye drops for inhibition of diabetic cataract in rats. METHODS Diabetes was induced in 69 male Sprague-Dawley rats by an intraperitoneal injection of streptozotocin (65 mg/kg body weight). One group (DV) of animals was treated by instillation of one drop of 0.2% RS-verapamil hydrochloride in both eyes three times daily for 8 weeks. The placebo trea...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2004

ISSN: 0007-1161

DOI: 10.1136/bjo.88.1.44